you are allergic to any ingredient in Plavix
you have an active bleeding disorder, such as a stomach ulcer or bleeding in the brain you are taking certain azole antifungals (eg, fluconazole, ketoconazole, voriconazole), cimetidine, etravirine, felbamate, fluoxetine, fluvoxamine, certain proton pump inhibitors (eg, omeprazole, esomeprazole), or ticlopidine.
Contact your doctor or health care provider right away if any of these apply to you.
Some medical conditions may interact with Plavix. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
if you are pregnant, planning to become pregnant, or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances
if you have bone marrow disease, liver or kidney problems, or a history of ulcers if you have had a recent injury or surgery, including dental surgery.
Some medicines may interact with Plavix. Tell your health care provider if you are taking any other medicines, especially any of the following:
Dabigatran, nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, ibuprofen), oral anticoagulants (eg, warfarin), or salicylates (eg, aspirin) because the risk of bleeding may be increased by Plavix
Azole antifungals (eg, ketoconazole), cimetidine, etravirine, felbamate, fluoxetine, fluvoxamine, proton pump inhibitors (eg, omeprazole), or ticlopidine because they may decrease Plavix's effectiveness
Fluvastatin, phenytoin, tamoxifen, tolbutamide, or torsemide because the risk of their side effects may be increased by Plavix.
This may not be a complete list of all interactions that may occur. Ask your health care provider if Plavix may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
Important safety information:
Plavix may cause dizziness. This effect may be worse if you take it with alcohol or certain medicines. Use Plavix with caution. Do not drive or perform other possible unsafe tasks until you know how you react to it.
Plavix may reduce the number of clot-forming cells (platelets) in your blood. Avoid activities that may cause bruising or injury. Tell your doctor if you have unusual bruising or bleeding. Tell your doctor if you have dark, tarry, or bloody stools.
Tell your doctor or dentist that you take Plavix before you receive any medical or dental care, emergency care, or surgery. You may need to stop Plavix before you have certain types of surgery.
Plavix must be converted in the body for it to work. This conversion does not occur as well in some people (about 2% of white patients, 4% of black patients, and 14% of Chinese patients). The medicine may not work as well in these patients. Your doctor may perform a test to check how well your body is able to convert Plavix. Talk with your doctor for more information.
Plavix should not be used in children; safety and effectiveness in children have not been confirmed.
Pregnancy and breast-feeding: If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using Plavix while you are pregnant. It is not known if Plavix is found in breast milk. Do not breastfeed while taking Plavix.
